بررسی غلظت IL-1? و IL-6 و IL-8 و TNF-? در کنسانتره های پلاکتی

Background: As increase of cytokines (like IL-1 , IL-6 , IL-8 and TNF- ) in platelet concentrates (PCs) during storage are involved in Febrile Non Hemolytic Transfusion Reactions (FNHTRs) after Platelet transfusion, the aim of this study was the survey of these cytokines level in PCs produced in Tehran Blood Center. Materials and Methods: This study proposed to determine if WBC reduction in P...

متن کامل

Interleukin 8 (IL-8) - a universal biomarker?

Many clinical conditions including various types of cancers are complex and generally require invasive, laborious, expensive and time-consuming investigations for their diagnosis, treatment and follow-up. There is therefore a general need for exploring non-invasive markers in clinical medicine. Interleukin 8 (IL-8) is currently being applied in various subspecialties of medicine either for the ...

متن کامل

Chemical makeover inhibits IL-8

Chemical makeover inhibits IL-8 On page 2085, Proost et al. find that altering a single arginine turns an inflammatory chemokine docile. The chemokine IL-8, which activates and recruits neutrophils, is secreted as a mixture of isoforms that vary in length due to proteolysis. A cut after the first five amino end residues produces active protein, whereas cuts elsewhere inhibit activity. Proteolys...

متن کامل

Modification of sulfhydryl groups of interleukin-8 (IL-8) receptor impairs binding of IL-8 and IL-8-mediated chemotactic response of human polymorphonuclear neutrophils.

Interleukin-8 (IL-8), a monocyte-derived neutrophil chemotactic agent, has a potential role in the regulation of inflammatory responses. The specific receptor for IL-8 has been identified and characterized on the surface of human neutrophils (Samanta, A. K., Oppenheim, J. J., and Matsushima, K. (1989) J. Exp. Med. 169, 1185-1189). The present study demonstrates that at least two sulfhydryl grou...

متن کامل

The role of cytokines in seizures: interleukin (IL)-1β, IL-1Ra, IL-8, and IL-10

Brain insults, including neurotrauma, infection, and perinatal injuries such as hypoxic ischemic encephalopathy, generate inflammation in the brain. These inflammatory cascades induce a wide spectrum of cytokines, which can cause neuron degeneration, have neurotoxic effects on brain tissue, and lead to the development of seizures, even if they are subclinical and occur at birth. Cytokines are s...

متن کامل

ذخیره در منابع من

ذخیره در منابع من قبلا به منابع من ذحیره شده

{@ msg_add @}

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Archives of Public Health

سال: 2020

ISSN: 1857-7148

DOI: 10.3889/aph.2020.4472